Effect of Running Training on White Blood Cells and Platelets Count and Red Blood Cells Distribution Width in Untrained Middle-Aged Men

Abstract

Background:  White blood cells count (WBC), platelet count (Plt) and red blood cells distribution width (RDW) are some emerging atherosclerosis risk factors. Objectives:  The purpose of this research was to study the effects of three months running exercise on these variables in untrained overweight middle-aged men. Methods:  Subjects were divided in groups of control (n = 10) and exercise (n = 11). In experimental group, subjects performed twelve weeks (three times per week) running exercise (intensity was between 75% to 85% of maximum heart rate). Blood samples were collected 24 hours before and 48 hours after exercises. Paired t-test was used for analysis of data in SPSS V. 15. Results:  Statistical analysis showed significant reduction of RDW and BMI, also significant elevation of WBC, Plt and VO₂max after three months exercise in the experimental group (P ≤ 0.05); no significant changes was observed in the control group (P > 0.05). Conclusions:  In general, three months running exercise may improve blood cells (leucocytes, erythrocytes and platelets) function that may lead to reduction of cardiovascular events risk in middle-aged men, but certainly more research is needed for precise conclusion.